SUMMARY Influenza poses a significant burden on society and health care systems. Although antivirals are an integral tool in effective influenza management, the potential for the emergence of antiviral-resistant viruses can lead to uncertainty and hesitation among front-line prescribers and policy makers. Here, we provide an overview of influenza antiviral resistance in context, exploring the key concepts underlying its development and clinical impact.

 

 

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Citation: Edward C. HolmesAeron C. HurtZuzana DobbieBarry ClinchJohn S. OxfordPedro A. Piedra