In 2019 a novel human pathogenic coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China , leading to a worldwide outbreak, declared a public health emergency of international concern on 30 January 2020  and a pandemic on 11 March 2020 . SARS-CoV-2 is a positive-stranded RNA virus from the species severe acute respiratory syndrome-related coronavirus, subgenus Sarbecovirus, genus Betacoronavirus, family Coronaviridae. The species contains a wide range of bat and human viruses including SARS-CoV-1 that caused an outbreak in 2002–03. The SARS-CoV-2 origins are still unknown, but zoonotic transmission, with bats (in particular Rhinolophus spp.) as the probable primary reservoir and other yet unknown animals as intermediate hosts, is considered the most likely route [4,5].
Citation:. Towards a sensitive and accurate interpretation of molecular testing for SARS-CoV-2: a rapid review of 264 studies. Euro Surveill. 2021;26(10):pii=2001134. https://doi.org/10.2807/1560-7917.ES.2021.26.10.2001134