Highlights

  • The majority of A. baumannii stains causing nosocomial pneumonia.are multi-drug resistant.
  • The overall mortality rate estimate for A. baumannii pneumonia is very high (∼43 %).
  • The prevalence rates of A. baumannii pneumonia are highly variable across the world.
  • The mortality rates of A. baumannii pneumonia are highly variable across the world.

Abstract

OBJECTIVE

The objective of this works was to assess the global prevalence of multidrug-resistance among A. baumannii causing hospital-acquired (HAP) and ventilator-associated pneumonia (VAP), and describe its associated mortality.

METHODS

We performed a systematic search of four databases for relevant studies. Meta-analysis was done based on United Nations geoscheme regions, individual countries and study period. We used a random-effects model to calculate pooled prevalence and mortality estimates with 95% confidence intervals (CIs), weighted by study size.

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