If cholesterol-lowering drugs are being impeded by the bacteria in some people’s guts, Sony Tuteja is hoping to work out how. Statins sometimes do a great job at reducing the amount of low-density lipoprotein (LDL), the ‘bad’ cholesterol that raises the risk of heart attacks and stroke, in the blood. But a lot of people see less of a benefit, and some none at all. In a 2016 study, 46% of those treated with the drug rosuvastatin saw their LDL drop by 50% or more1. But 43% saw a less than 50% decrease, and 11% had no reduction, or even had an increase in LDL.

 

Maksym Kozlenko [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], from Wikimedia Commons

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