The US Centers for Disease Control and Prevention (CDC) released new numbers today about tuberculosis (TB) in the United States in advance of World TB Day, which takes place on Mar 24, noting that cases have reached an all-time low.

In 2018 the CDC noted a total of 9,029 new TB cases in the United States, representing a 0.7% decrease from 2017. The incidence in 2018 was 2.8 per 100,000 persons, which is the lowest number recorded since the CDC began tracking TB in 1953.

The findings were published today in Morbidity and Mortality Weekly Report (MMWR).

But the incidence of TB among foreign-born residents of the US is preventing total elimination of the disease. And without a big increased investment in detection and treatment of latent TB infection (LTBI), the US will not see the elimination of TB in the 21st century, the authors said.

TB is 14 times more likely to be diagnosed in foreign-born residents than those born in the United States, the CDC said. In 2018, approximately two-thirds of new TB cases (6,276 [69.5%]) occurred in non–US-born persons, whereas 2,662 (29.5%) occurred in US-born persons.

In 46.3% of new TB cases diagnosed among foreign-born residents, the disease was diagnosed 10 or more years after the patient first arrived in America. That finding is consistent with data which shows the reactivation of remotely acquired LTBI has been responsible for more 80% of domestic TB cases in the US.

Mexico, the Philippines, India, Vietnam, and China are the top five countries of birth of non–U.S.-born persons with TB.

Read more at CIDRAP…

See also:

Mar 22 MMWR US TB study

Mar 22 MMWR global TB study

Mar 21 Eurosurveillance study