(CNN)It took just one day of use for several common sunscreen ingredients to enter the bloodstream at levels high enough to trigger a government safety investigation, according to a pilot study conducted by the Center for Drug Evaluation and Research, an arm of the US Food and Drug Administration.

The study, published Monday in the medical journal JAMA, also found that the blood concentration of three of the ingredients continued to rise as daily use continued and then remained in the body for at least 24 hours after sunscreen use ended.

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