Rigorous study shows depression and anxiety symptoms worsened among medical residents in Shanghai, and fear of workplace violence doubled, in early 2020. They worked in hospitals hundreds of miles from the epicenter of COVID-19. Their city of 24 million people locked down hard enough, and did enough testing, that it only had a few hundred cases of the disease. But hundreds of young Chinese doctors in a new study still experienced a sharp drop in mood, a rise in depression and anxiety symptoms, and a doubling of their fear of workplace violence, in just the first month of the coronavirus pandemic. The new findings, published in JAMA Network Open by an American and Chinese team, show in stark terms the potential mental toll of being a frontline healthcare worker in the time of COVID-19.