An international team of scientists have observed a previously unclear inflammatory mechanism caused by airborne particles that can worsen asthma symptoms, it has been reported in Toxicological Sciences.

As the world gets more and more industrialized, the risk of developing respiratory diseases increases. Very small particles released from industry and vehicle fumes are harmful to our health but exactly how is still unclear. In a collaborative study, researchers in Japan, the US and Germany have uncovered one mechanism that can exaggerate inflammation in response to diesel fumes and worsen symptoms of respiratory diseases.

Tiny particles in the air are released from vehicles with diesel exhausts, factories or urban landscapes. People living in urban or industrial areas have a higher risk of developing diseases such as asthma. However, the mechanism behind how asthma develops is very complicated, explains Associate Professor Yasuhiro Ishihara of the Graduate School of Integrated Sciences for Life, Hiroshima University. Many different factors can trigger asthma, such as genetics and allergies, but Ishihara speculates that:

“If we know the mechanism maybe we can prevent particle-induced asthma.”

 

iStock, curtoicurto

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