Scientists have created a new way to edit DNA that appears to make it even easier to precisely and safely re-write genes.

The new technique, called prime editing, is designed to overcome some of the limitations of CRISPR. That technique, often described as a kind of molecular scissors for genes, has been revolutionizing scientific research by letting scientists alter DNA.

“It’s proven difficult to use these molecular scissors to make precise DNA changes in most cell types,” says David Liu, a biologist at Harvard, MIT and the Broad Institute in Cambridge, Mass.

Liu heads the lab where the new prime editing technique was created in research led by Andrew Anzalone. The advance is described in the journal Nature, in an article published Monday.

 

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