Findings from a trio of recently published studies shed new light on the mobile colistin-resistance gene MCR in Latin America, including one spotlighting the first detections of MCR-1 in Escherichia coli in Uruguay.

A second report is a research letter detailing the spread of the MCR-5 gene on Paraguay’s poultry farms. And the third is a review of available data on MCR gene dissemination in Latin America and the Caribbean, which found an overall frequency of 2.9% in bacteria isolates collected from 2000 through 2018.

Colistin is considered a last-resort antibiotic, used to treat difficult-to-treat multidrug-resistant infections.

Uruguay findings from hospital patients


Credit: Elizabeth H. White, M.S.

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