Background The use of extracorporeal membrane oxygenation (ECMO) in critically ill adults is increasing. There are currently no guidelines for antimicrobial prophylaxis. We analyzed 7 years of prophylactic antimicrobial use across three time series for patients on ECMO at our institution in the development, improvement, and streamlining of our ECMO antimicrobial prophylaxis protocol.

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Citation: Aditya Shah, MBBS, Priya Sampathkumar, MD, Ryan W Stevens, Pharm.D, John K Bohman, MD, Brian D Lahr, MS, Prabij Dhungana, MBBS, Kirtivardhan Vashistha, MBBS, John C O’Horo, MD MPH, Reducing Broad Spectrum Antimicrobial Use in Extracorporeal Membrane Oxygenation (ECMO): Reduce AMMO Study, Clinical Infectious Diseases, 2021;, ciab118, https://doi.org/10.1093/cid/ciab118