Abstract

Neural control of the function of visceral organs is essential for homeostasis and health. Intestinal peristalsis is critical for digestive physiology and host defence, and is often dysregulated in gastrointestinal disorders1. Luminal factors, such as diet and microbiota, regulate neurogenic programs of gut motility2,3,4,5, but the underlying molecular mechanisms remain unclear.

 

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Citation:  Obata, Y., Castaño, Á., Boeing, S. et al. Neuronal programming by microbiota regulates intestinal physiology. Nature 578, 284–289 (2020). https://doi.org/10.1038/s41586-020-1975-8