Implementation of a national safety program that helps US hospitals to establish antibiotic stewardship programs (ASPs) and clinicians to improve their antibiotic decision-making was associated with reduced antibiotic use and fewer hospital-onset Clostridioides difficile infections, according to a study today in JAMA Network Open. The study, conducted by researchers with the Johns Hopkins University School of Medicine, the University of Chicago, and the Agency for Healthcare Research and Quality (AHRQ), evaluated the impact of AHRQ’s Safety Program for Antibiotic Use, which was established in 2017 to support hospitals in their efforts to establish ASPs and successfully implement stewardship principles. ASPs have been associated with reduced antibiotic use in individual hospitals across the country.

 

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