Ghana falls within the WHO hotspot for antimicrobial resistance (AMR) emergence in Sub-Saharan Africa1. Concerted efforts are therefore being made to contain the public health challenges posed by drug-resistant bacteria in Ghana. Leveraging on the concept of the ‘One Health’ approach and strategies2, the Ghanaian government has introduced a National AMR Action Plan3 in alignment with the Sustainable Development Goal Agenda 3 (well-being and upgraded standard of health) to fight AMR and reduce its burden. It is important that these antibiotic salvaging initiatives and approaches are consistently efficient and progressively effective. Initiatives, such as those led by the Fleming Fund Country Grant, reveal the urgent need to introduce the right practices into national AMR surveillance4.