•    People spend 1/3rd of their lives sleeping and human exposures to indoor air pollutants during sleep periods may play an important role in human health and sleep quality. This review provides an introduction to IAQ in sleep microenvironments and highlights future research needs.
•    Beds and pillows serve as settled dust reservoirs for a complex mixture of bacteria, fungi, allergens, and particle-bound semi-volatile organic compounds (SVOCs), which can be readily stirred-up, or resuspended, upon tossing and turning during sleep.
•    Bedding products, such as crib mattresses and frames, emit a variety of VOCs and SVOCs into the air around a sleeping person, including phenol, styrene, formaldehyde, phthalate and alternative plasticizers, and brominated and organophosphate flame retardants.
•    Human exposure to mattress-released pollutants is amplified by the source-proximity effect of the sleep microenvironment due to the close and intimate contact of the human body with the bed.

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