Highlights

  • Genome-wide CRISPR screens for SARS-CoV-2 and seasonal coronavirus host factors
  • Identification of host factors and pathways with pan-coronavirus and discrete roles
  • Coronaviruses co-opt multiple biological pathways
  • TMEM41B is a critical pan-coronavirus host factor

    ViktoriaAnselm [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], from Wikimedia Commons

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