Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks

Highlights

Genome-wide CRISPR screens for SARS-CoV-2 and seasonal coronavirus host factors
Identification of host factors and pathways with pan-coronavirus and discrete roles
Coronaviruses co-opt multiple biological pathways
TMEM41B is a critical pan-coronavirus host factor

ViktoriaAnselm [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], from Wikimedia Commons