Epidemiology of Invasive Escherichia coli Infection and Antibiotic Resistance Status among Patients Treated in U.S. Hospitals: 2009–2016

Published data is limited on the prevalence and risk of recurrence of extraintestinal invasive E. coli infections (IEIs) in the United States.

All inpatient and hospital-based outpatient visits occurring between 2009−2016 at hospitals with continuous microbiology data submission to the Premier Healthcare Database for 90 days prior to the admission/visit and 12 months following it were included in analysis. IEI was defined as having positive E. coli culture from a normally sterile site (e.g., blood, cerebrospinal fluid). Prevalence of IEI, 12-month risk of recurrent IEI, and antibiotic resistance were assessed.