WASHINGTON, D.C. – Misleading information on the relationship between smoking and COVID-19 has been reported by the media following the release of two linked papers on an open-access website, Qeios. As a result, it has been widely and inaccurately reported that these papers demonstrate that smokers are at lower risk of COVID-19 and by implication that nicotine may offer protection from COVID-19. This conclusion is inconsistent with the growing number of studies that smokers are at greater risk of suffering more severe consequences of COVID-19, has been derived from results that have not been peer-reviewed, and does not stand up to scientific scrutiny. The French statistics released on Qeios scientifically do not permit any form of credible conclusions on smoking, nicotine and COVID-19. The studies have significant weaknesses, including the fact they rely on a very small sample size that does not involve a representative sample, does not take into account data regarding ex-smokers, or account for significant potential confounding factors.