Centauri’s novel one-two approach kills bacteria and redirects the immune system to selectively kill superbugs

(BOSTON, MA) – CARB-X is awarding Centauri Therapeutics of Sandwich, UK, up to $1.4 million in non-dilutive funding to develop a novel dual-acting immunotherapy to treat serious infections caused by Gram-negative pathogens, including drug-resistant strains of Enterobacteriaceae, P. aeruginosa, and A.baumannii.

“Centauri’s project is an exciting new approach to treating drug-resistant Gram-negative bacterial infections, and adds rich diversity to CARB-X’s early development portfolio of antibiotics, vaccines, rapid diagnostics and other life-saving products,” said Erin Duffy, Chief of Research and Development of CARB-X, which is based at Boston University School of Law in Boston USA.  “Projects in the Powered by CARB-X portfolio are in the early stages of development, but if successful, each offers tremendous hope and progress in the global fight against drug resistance. CARB-X is led by Boston University and funded by a global partnership.


Credit: iStock, MacXever

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