Just when you think the numbers can’t get any worse, they do. December 2020 was the cruelest month when it came to coronavirus disease 2019 (COVID-19), that is until January 2021 came along. The United States topped 200,000 new COVID-19 infections yesterday for the seventh day in a row. In addition, the US has averaged more than 3000 COVID-19 deaths a day over the past week, according to Johns Hopkins University. Experts interviewed by Infection Control Today® warned that the public should have greatly curtailed participation in social gatherings over the holidays and that might have happened to some extent, but not to the extent needed to avoid what could become one of the most brutal winters in US history from a public health standpoint.