Toothpaste and hand wash are causing antibiotic resistance

By | 2018-06-20T11:24:23+00:00 June 20th, 2018|

A common ingredient in toothpaste and hand wash could be contributing to antibiotic resistance, according to University of Queensland research. A study led by Dr Jianhua Guo from UQ's Advanced Water Management Centre focused on triclosan, a compound used in more than 2000 personal care products. Dr Guo said while it was well-known the overuse [...]

US military wants to know what synthetic-biology weapons could look like

By | 2018-06-20T11:08:54+00:00 June 20th, 2018|

A study ordered by the US Department of Defense has concluded that new genetic-engineering tools are expanding the range of malicious uses of biology and decreasing the amount of time needed to carry them out. The new tools aren’t in themselves a danger and are widely employed to create disease-resistant plants and new types of medicine. [...]

Does Isolating Clostridium Difficile Carriers Shorten Outbreak Duration?

By | 2018-06-19T11:51:12+00:00 June 19th, 2018|

Isolating Clostridium difficile carriers during an outbreak is not associated with a significantly shorter outbreak duration, according to results published in Clinical Infectious Diseases. The study aimed to investigate the impact of screening and isolating C difficile carriers during C difficile infection (CDI) outbreaks. The study included all patients present on a ward during an outbreak, including a total of 4 outbreaks [...]

Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome

By | 2018-06-19T11:41:36+00:00 June 19th, 2018|

Abstract Introduction The emergence of MDR-TB remained a major public health threat particularly in developing countries. With increased prevalence and complexity of treatment, the burden of MDR-TB challenged the country. It is of an important; the epidemiology of drug resistant TB is not well understood. There are few studies conducted to assess the prevalence, determinants [...]

CrpP Is a Novel Ciprofloxacin-Modifying Enzyme Encoded by the Pseudomonas aeruginosa pUM505 Plasmid

By | 2018-06-19T11:17:44+00:00 June 19th, 2018|

ABSTRACT The pUM505 plasmid, isolated from a clinical Pseudomonas aeruginosa isolate, confers resistance to ciprofloxacin (CIP) when transferred into the standard P. aeruginosa strain PAO1. CIP is an antibiotic of the quinolone family that is used to treat P. aeruginosa infections. In silico analysis, performed to identify CIP resistance genes, revealed that the 65-amino-acid product encoded by the orf131 [...]

Rift Valley fever – Kenya

By | 2018-06-19T04:37:07+00:00 June 19th, 2018|

On 8 June 2018, the Ministry of Health (MoH) for Kenya confirmed an outbreak of Rift Valley fever. The first patient was admitted to a hospital in Wajir County in north-eastern Kenya on 2 June with fever, body weakness, and bleeding from the gums and mouth. The patient reported having consumed meat from a sick [...]

More suspected Ebola cases noted, but total holds steady

By | 2018-06-19T04:24:08+00:00 June 19th, 2018|

The Democratic Republic of the Congo (DRC) announced 11 new suspected cases of Ebola over the weekend in Bikoro and Iboko, the remote health zones where the current outbreak began in the middle of May, but the outbreak total has not risen. The case count now stands at 64 cases (38 confirmed, 14 probable, and [...]

MERS in Saudi Arabia this year includes hospital and household clusters

By | 2018-06-19T04:20:24+00:00 June 19th, 2018|

In a profile of MERS-CoV activity in Saudi Arabia since Jan 12, the country has reported 75 cases, including 10 from two small hospital clusters and 11 from two household clusters, the World Health Organization (WHO) said today. The most recent MERS-CoV (Middle East respiratory syndrome coronavirus) cluster involves a household in Najran, which an [...]

Mycobacterium tuberculosis Pst/SenX3-RegX3 Regulates Membrane Vesicle Production Independently of ESX-5 Activity

By | 2018-06-19T04:10:48+00:00 June 19th, 2018|

ABSTRACT Mycobacterium tuberculosis releases membrane vesicles (MV) that modulate host immune responses and aid in iron acquisition, although they may have additional unappreciated functions. MV production appears to be a regulated process, but virR remains the only characterized genetic regulator of vesiculogenesis. Here, we present data supporting a role for the M. tuberculosis Pst/SenX3-RegX3 signal transduction system in regulating MV [...]