About James Sweeney

This author has not yet filled in any details.
So far James Sweeney has created 7827 blog entries.

S. aureus found in abundance on ICU stethoscopes

By |2018-12-14T14:53:52+00:00December 14th, 2018|

At minimum, more than half of the stethoscopes sampled at a Philadelphia hospital tested positive for Staphylococcus aureus, and many were also contaminated with Pseudomonas and Acinetobacter bacteria, indicating that the instruments are a potential vector for hospital-acquired infections, researchers reported. Ronald G. Collman , MD, professor of medicine, pulmonary, allergy and critical care at the University of Pennsylvania Perelman School of Medicine, and colleagues [...]

Developing a next-generation whooping cough vaccine

By |2018-12-14T14:35:33+00:00December 14th, 2018|

Tulane University researchers are using nanoparticles from bacteria to develop a more effective and longer lasting vaccine against pertussis. The National Institutes of Health awarded microbiologist Lisa Morici and immunologist James McLachlan a contract for up to $8.5 million over five years for the project. Their vaccine uses outer membrane vesicles (OMVs) from bacteria to [...]

Japanese woman died from tick-borne illness after cat bite, health ministry says

By |2018-12-14T14:31:48+00:00December 14th, 2018|

A woman in western Japan died from a tick-borne disease last year after being bitten by a stray cat, the health ministry said. The case is believed to be the world’s first human infection of the illness without a direct bite from a tick. The ministry said Monday that the woman in her 50s was [...]

Study supports shorter antibiotic treatment for bacteremia

By |2018-12-14T14:23:05+00:00December 14th, 2018|

Results from a randomized controlled trial of patients with bloodstream infections indicate that treatment with a 7-day course of antibiotics is non-inferior to a 14-day course, a finding that could have important implications for antibiotic stewardship. The findings, published yesterday in Clinical Infectious Diseases, are significant because shortening antibiotic therapy is seen as an important tool for [...]

Ebola outbreak grows as DRC issues alerts in Goma

By |2018-12-14T14:11:23+00:00December 14th, 2018|

The Democratic Republic of the Congo's (DRC's) health ministry today in its daily Ebola update reported 5 new cases and 9 new deaths and added that 100 suspected cases are under investigation. Outbreak totals now stand at 505 cases, including 298 deaths. The new cases include two in Katwa and one each in Komanda, Musienene, [...]

Klebsiella pneumoniae causing urinary tract infections in companion animals and humans: population structure, antimicrobial resistance and virulence genes

By |2018-12-12T21:26:38+00:00December 12th, 2018|

Abstract Objectives To characterize the population structure, antimicrobial resistance and virulence genes of Klebsiella spp. isolated from dogs, cats and humans with urinary tract infections (UTIs). Methods Klebsiella spp. from companion animals (n = 27) and humans (n = 77) with UTI were tested by the disc diffusion method against 29 antimicrobials. Resistant/intermediate isolates were tested by PCR for 16 resistance genes. [...]

McDonald’s sets timeline to cut antibiotics in beef supply

By |2018-12-12T21:16:05+00:00December 12th, 2018|

Editor's note: This story was updated later on Dec 11 with comments from Paul Plummer, DVM. McDonald's today announced a new policy to reduce the use of medically important antibiotics in its beef supply chain. The company says it will partner with supplying beef producers in the United States and nine other countries—Australia, Brazil, Canada, France, [...]

Ebola count in DRC hits 500 in growing outbreak

By |2018-12-12T21:08:12+00:00December 12th, 2018|

The world's second-largest Ebola outbreak hit another milestone today, as the Democratic Republic of the Congo (DRC) recorded 2 new cases, raising outbreak totals to 500, including 289 deaths. Of the four new deaths recorded today, two are community deaths in Beni and Mabalako, which took place outside a hospital or Ebola treatment center, raising [...]

Binning microbial genomes using deep learning

By |2018-12-12T20:59:43+00:00December 12th, 2018|

Abstract Identification and reconstruction of microbial species from metagenomics wide genome sequencing data is an important and challenging task. Current existing approaches rely on gene or contig co-abundance information across multiple samples and k-mer composition information in the sequences. Here we use recent advances in deep learning to develop an algorithm that uses variational autoencoders [...]

What’s holding pharma back from the next antibiotic breakthrough?

By |2018-12-12T19:35:33+00:00December 12th, 2018|

By PETER BAK DECEMBER 10, 2018 In the five years since the alarm sounded about so-called superbugs, the world has continued to grapple with the staggering health and economic impacts of antibiotic resistance and mounting resistance to antibiotics of last resort. In the U.S. alone, antibiotic resistance adds $20 billion to $35 billion in direct health care costs each year, along with [...]