About James Sweeney

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So far James Sweeney has created 5129 blog entries.

Mycobacterium tuberculosis Pst/SenX3-RegX3 Regulates Membrane Vesicle Production Independently of ESX-5 Activity

By | 2018-06-19T04:10:48+00:00 June 19th, 2018|

ABSTRACT Mycobacterium tuberculosis releases membrane vesicles (MV) that modulate host immune responses and aid in iron acquisition, although they may have additional unappreciated functions. MV production appears to be a regulated process, but virR remains the only characterized genetic regulator of vesiculogenesis. Here, we present data supporting a role for the M. tuberculosis Pst/SenX3-RegX3 signal transduction system in regulating MV [...]

Study IDs significant infection control gaps at small rural hospitals

By | 2018-06-19T04:01:02+00:00 June 19th, 2018|

Critical access hospitals struggle with infection prevention and control, especially when it comes to injection safety and preventing certain infections, according to findings presented at the annual conference of the Association for Professionals in Infection Control and Epidemiology, or APIC. “Lack of competency-based training programs and failure to perform audits and feedback appear to be [...]

Resilience: A skill your child really needs to learn (and what you can do to help)

By | 2018-06-19T03:49:56+00:00 June 19th, 2018|

It’s the end of the school year, the time of graduation speeches, of looking back at accomplishments and making plans for new ones. It’s a time when many parents think about their hopes and dreams for their children, whether they are graduating or just learning to walk. As parents, we tend to think about getting [...]

CDC Announces Multistate Salmonella Outbreak Linked With Kellogg’s Honey Smacks Cereal

By | 2018-06-19T03:42:33+00:00 June 19th, 2018|

The US Centers for Disease Control and Prevention (CDC) is investigating yet another multistate outbreak of Salmonella. Where last week, a multistate outbreak of Salmonella Adelaide had been traced back to pre-cut melon produced and distributed by Caito Foods LLC, this new outbreak has been linked with a breakfast favorite: Kellogg’s Honey Smacks cereal. As of June 14, 2018, 73 [...]

Characteristics of the antibiotic regimen that affect antimicrobial resistance in urinary pathogens

By | 2018-06-19T03:34:25+00:00 June 19th, 2018|

Abstract Background Treatment duration, treatment interval, formulation and type of antimicrobial (antibiotic) are modifiable factors that will influence antimicrobial selection pressure. Currently, the impact of the route of administration on the occurrence of resistance in humans is unclear. Methods In this retrospective multi-center cohort study, we assessed the impact of different variables on antimicrobial resistance [...]

North Dakota reports 1st human West Nile virus case in Ramsey County

By | 2018-06-19T02:12:14+00:00 June 19th, 2018|

The North Dakota Department of Health (NDDoH) has confirmed the first human case of West Nile virus (WNV) disease for the season. Additionally, a pool of mosquitos has tested positive for WNV in Grand Forks. The individual resides in Ramsey County and was not hospitalized for their illnesses. In 2017, the NDDoH received reports that [...]

DRC bordering countries begin Ebola preparedness training

By | 2018-06-18T23:57:10+00:00 June 18th, 2018|

WASHINGTON — The Ebola outbreak in the Democratic Republic of the Congo continues more than one month after being confirmed by the World Health Organization. And while health workers and international aid organizations fight to contain the virus, WHO has focused its most recent efforts on Ebola preparedness training in neighboring countries. In Republic of Congo, more than 50 [...]

Do we keep waiting for the next pandemic or try to prevent it?

By | 2018-06-18T14:30:40+00:00 June 18th, 2018|

News of the latest Ebola outbreak in the Democratic Republic of the Congo is an urgent reminder that we need to change the way we fight disease, and we need to do so now. Over the last few decades, the number of disease outbreaks has more than tripled, culminating in three major epidemics in recent years — Ebola, yellow [...]

Searching for a change: The need for increased support for public health and research on fungal diseases

By | 2018-06-18T14:26:50+00:00 June 18th, 2018|

Introduction: The threat of fungal diseases Fungal diseases have been continually neglected over the years despite their alarming impact on human health. Recent estimates [1] suggest a global annual occurrence of approximately 3,000,000 cases of chronic pulmonary aspergillosis, more than 200,000 cases of cryptococcal meningitis, 700,000 cases of invasive candidiasis, 500,000 cases of Pneumocystis jiroveciipneumonia, 250,000 [...]